Diabetes defect defined

A Novel Cellular Defect in Diabetes

OBJECTIVE Skeletal muscle myopathy is a common diabetes complication. One possible cause of myopathy is myocyte failure to repair contraction-generated plasma membrane injuries. Here, we test the hypothesis that diabetes induces a repair defect in skeletal muscle myocytes. RESEARCH DESIGN AND METHODS Myocytes in intact muscle from type 1 (INS2(Akita+/-)) and type 2 (db/db) diabetic mice were ...

Peripheral Neuropathy Defined by Monofilament Insensitivity and Diabetes Status

OBJECTIVE To determine whether diabetes status, including prediabetes, is associated with increased risk of peripheral neuropathy as defined by monofilament insensitivity. RESEARCH DESIGN AND METHODS This study used data from the 1999-2004 National Health and Nutrition Examination Survey (n = 7,818). Peripheral neuropathy was defined as one or more insensate sites detected by a Semmes-Weinste...

Epidemiology of diabetes in a well defined population in Sweden The Skaraborg Diabetes Registry

Algebras defined by homomorphisms

Let $mathcal{R}$ be a  commutative ring with identity, let $A$ and $B$ be two $mathcal{R}$-algebras and $varphi:Blongrightarrow A$ be an $mathcal{R}$-additive algebra homomorphism. We introduce a new algebra $Atimes_varphi B$, and give some basic properties of this algebra. Generalized $2$-cocycle derivations on $Atimes_varphi B$ are studied. Accordingly, $Atimes_varphi B$ is considered from th...

Genetic forms of nephrogenic diabetes insipidus (NDI): Vasopressin receptor defect (X-linked) and aquaporin defect (autosomal recessive and dominant).

Nephrogenic diabetes insipidus (NDI), which can be inherited or acquired, is characterized by an inability to concentrate urine despite normal or elevated plasma concentrations of the antidiuretic hormone, arginine vasopressin (AVP). Polyuria with hyposthenuria and polydipsia are the cardinal clinical manifestations of the disease. About 90% of patients with congenital NDI are males with X-link...